Once a rising star in the New York City medical community, Hank found himself out of work, dumped by his fiancée and out of options after a dustup with some hospital honchos. Fed up with Hank's personal pity-party, his younger brother, Evan (Paulo Costanzo), convinced Hank to join him on a last-minute trip to the Hamptons for Memorial Day weekend. When the brothers crashed a party at the home of a Hamptons billionaire and a guest fell critically ill, Hank saved the day. His dramatic medical rescue drew attention from the crowd, and soon Hank's phone started ringing off the hook with patients wanting Hank to make house calls. By the end of the weekend, HankMed was born. With Evan as the company's CFO and the whip-smart, ambitious Divya (Reshma Shetty) as Hank's physician's assistant, Hank becomes the Hamptons' new in-demand Doctor-for-Hire. News travels fast on the East End, especially when it's about a talented young doctor with MacGyver-like skills who makes house calls. But the rich and powerful aren't the only ones seeking out HankMed's services; there are plenty of less well-off locals who need his help, too, and he's more than happy to lend a hand. As the practice grows and they become more settled in their new lives, the brothers begin to experience growing pains. With their unreliable father Eddie (Henry Winkler) back in their lives, Evan's recent engagement to Paige (Brooke D'Orsay) and Jill (Jill Flint) about to leave Hamptons Heritage, Hank and Evan quickly learn that life in the Hamptons isn't always a walk on the beach.